Scientific Name: Mus musculus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae-> Mus-> Mus
Summary: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011] [NCBI] [Proteinatlas]
Data set information
Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
---|---|---|---|---|---|---|
Vthunter_110001 | 2018.02 | Microwell-seq | Bladder | Normal | 2746 | Link |
Vthunter_110002 | 2018.02 | Microwell-seq | BoneMarrow | Normal | 510 | Link |
Vthunter_110003 | 2018.02 | Microwell-seq | BoneMarrowcKit | Normal | 5298 | Link |
Vthunter_110004 | 2018.02 | Microwell-seq | BoneMarrowcKit | Normal | 13019 | Link |
Vthunter_110005 | 2018.02 | Microwell-seq | BoneMarrowcKit | Normal | 8166 | Link |
Vthunter_110006 | 2018.02 | Microwell-seq | Brain | Normal | 3285 | Link |
Vthunter_110007 | 2018.02 | Microwell-seq | Brain | Normal | 753 | Link |
Vthunter_110010 | 2018.02 | Microwell-seq | Fetal FemaleGonad | Normal | 8462 | Link |
Vthunter_110011 | 2018.02 | Microwell-seq | Fetal Intestine | Normal | 6076 | Link |
Vthunter_110012 | 2018.02 | Microwell-seq | Fetal Lung | Normal | 6453 | Link |
Vthunter_110014 | 2018.02 | Microwell-seq | Fetal Stomach | Normal | 6192 | Link |
Vthunter_110015 | 2018.02 | Microwell-seq | Kidney | Normal | 4682 | Link |
Vthunter_110016 | 2018.02 | Microwell-seq | Liver | Normal | 4424 | Link |
Vthunter_110017 | 2018.02 | Microwell-seq | Liver | Normal | 261 | Link |
Vthunter_110018 | 2018.02 | Microwell-seq | Lung | Normal | 2512 | Link |
Vthunter_110019 | 2018.02 | Microwell-seq | Lung | Normal | 1414 | Link |
Vthunter_110020 | 2018.02 | Microwell-seq | Lung | Normal | 3014 | Link |
Vthunter_110021 | 2018.02 | Microwell-seq | MammaryGland.Involution | Normal | 3510 | Link |
Vthunter_110022 | 2018.02 | Microwell-seq | MammaryGland.Involution | Normal | 1311 | Link |
Vthunter_110023 | 2018.02 | Microwell-seq | MammaryGland.Lactation | Normal | 6633 | Link |
Vthunter_110024 | 2018.02 | Microwell-seq | MammaryGland.Lactation | Normal | 6905 | Link |
Vthunter_110025 | 2018.02 | Microwell-seq | MammaryGland.Pregnancy | Normal | 4909 | Link |
Vthunter_110026 | 2018.02 | Microwell-seq | MammaryGland.Virgin | Normal | 2081 | Link |
Vthunter_110027 | 2018.02 | Microwell-seq | MammaryGland.Virgin | Normal | 1059 | Link |
Vthunter_110028 | 2018.02 | Microwell-seq | MammaryGland.Virgin | Normal | 648 | Link |
Vthunter_110029 | 2018.02 | Microwell-seq | MammaryGland.Virgin | Normal | 1592 | Link |
Vthunter_110035 | 2018.02 | Microwell-seq | NeonatalCalvaria | Normal | 3617 | Link |
Vthunter_110039 | 2018.02 | Microwell-seq | NeonatalPancreas | Normal | 4571 | Link |
Vthunter_110040 | 2018.02 | Microwell-seq | NeonatalRib | Normal | 1217 | Link |
Vthunter_110041 | 2018.02 | Microwell-seq | NeonatalRib | Normal | 3082 | Link |
Vthunter_110043 | 2018.02 | Microwell-seq | NeonatalSkin | Normal | 3392 | Link |
Vthunter_110044 | 2018.02 | Microwell-seq | Ovary | Normal | 1931 | Link |
Vthunter_110045 | 2018.02 | Microwell-seq | Pancreas | Normal | 3610 | Link |
Vthunter_110046 | 2018.02 | Microwell-seq | PeripheralBlood | Normal | 3201 | Link |
Vthunter_110047 | 2018.02 | Microwell-seq | PlacentaE14.1 | Normal | 1873 | Link |
Vthunter_110048 | 2018.02 | Microwell-seq | PlacentaE14.2 | Normal | 2473 | Link |
Vthunter_110049 | 2018.02 | Microwell-seq | Prostate | Normal | 1031 | Link |
Vthunter_110050 | 2018.02 | Microwell-seq | Prostate | Normal | 1474 | Link |
Vthunter_110051 | 2018.02 | Microwell-seq | SmallIntestine | Normal | 3438 | Link |
Vthunter_110052 | 2018.02 | Microwell-seq | SmallIntestine | Normal | 1671 | Link |
Vthunter_110053 | 2018.02 | Microwell-seq | SmallIntestine | Normal | 1575 | Link |
Vthunter_110054 | 2018.02 | Microwell-seq | Spleen | Normal | 1970 | Link |
Vthunter_110055 | 2018.02 | Microwell-seq | Stomach | Normal | 2389 | Link |
Vthunter_110056 | 2018.02 | Microwell-seq | Testis | Normal | 2216 | Link |
Vthunter_110057 | 2018.02 | Microwell-seq | Testis | Normal | 11789 | Link |
Vthunter_110058 | 2018.02 | Microwell-seq | TrophoblastStemCells | Normal | 19489 | Link |
Vthunter_110059 | 2018.02 | Microwell-seq | Uterus | Normal | 2035 | Link |
Vthunter_110060 | 2018.02 | Microwell-seq | Uterus | Normal | 1704 | Link |
Vthunter_110066 | 2019.12 | MARS-seq | TotalBrain | Normal | 2304 | Link |
Vthunter_110105 | 2018.07 | 10X Genomics | Adipose | Adipose | 288 | Link |
Vthunter_110106 | 2016.02 | 10X Genomics | PrimaryVisualCortex | PrimaryVisualCortex | 1787 | Link |
Featureplot of receptors
Expression: Biased expression in skin (RPKM 30.6), esophagus (RPKM 23.7) and 7 other tissues